A Sainik School alumnus, Indrajith had his degree in Computer science from Tirunalveli Engineering College. He joined Nexage as a software personal before going into acting, where he first appeared in a television film Annie. He is married to actress Poornima Mohan. They have a daughter named Prarthana.He debuted in the film Ooomappenninu Uriyadappayyan directed by Vinayan. He was noted for his villain role in the blockbuster Meesamadhavan, directed by Lal Jose. He has recently debuted in Tamil. He acted alongside Mohanlal in Anwar Rasheed's Chotta Mumbai and Shaji Kailas's Baba Kalyani. His performance as the villain in Baba Kalyani was acclaimed by critics. He also acted in Lal Jose's superhit Arabikatha and Santhosh Sivan's first Hollywood movie Road to the Top. He paired with his brother Prithviraj Sukumaran in several films including the 2006 blockbuster Classmates (film).