Reema Sen was born in Kolkata, into a middle class family in 1981. She completed high school from Calcutta, after which her family moved to Mumbai. In Mumbai, she began her modelling career, appearing in a number of advertising campaigns. Later on, Reemma moved from modelling to acting soon after. Her first film was a low budget film, Chitram, in Telugu, in which she acted opposite Uday Kiran. Later she appeared in the Tamil film, Minnale, which was very successful. She tried to enter Bollywood but her first Hindi film Hum Ho Gaye Aapke flopped, and she decided to continue working in Tamil cinema. Her latest movie Rendu was also a successful movie in the Tamil cinema. People found her facial expressions in the film Thimiru endearing and her horrific turn in Vallavan exposed her abilities in the histrionic department.Her role in Aayirathil Oruvan was highly praised by viewers and critics.